The South African Tuberculosis Vaccine Initiative (SATVI), is a world leader in TB vaccine clinical research located within the Health Sciences Faculty at the University of Cape Town.

The mission of SATVI  is the development of new and effective vaccination strategies against tuberculosis (TB). A new, effective vaccine has the potential to save hundreds of thousands of lives world-wide. We are testing multiple new vaccine candidates in clinical trials. We are also completing projects to address critical clinical, epidemiological, immunological and human genetic questions in TB vaccine development. Our activities are within an academic context, and thus include the training of postgraduate students. The SATVI field site is located in the Boland region, 110km outside Cape Town, where the rate of TB is amongst the highest recorded in the world. This rural area of about 12,000 square kilometers has a population of about 350,000, of whom more than 20,000 have participated in our studies to date.  

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